Interferon Regulatory Factor 5 Recombinant Protein 92-075 from ProSci, Inc

Description

Interferon Regulatory Factor 5 (IRF5) is a member of the IRF family. It contains one IRF tryptophan pentad repeat DNA-binding domain. IRF5 shuttles between the nucleus and the cytoplasm. IRF5 can form homodimer when it is phosphorylated. IRF5 functions as a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. Genetic variations in IRF5 are associated with susceptibility to systemic lupus erythematosus type 10. In addition, the genetic variations wil result in susceptibility to rheumatoid arthritis

Product Specs
ItemInterferon Regulatory Factor 5 Recombinant Protein
CompanyProSci, Inc
Price Pricing Info Supplier Page View Company Product Page
Catalog Number92-075
Quantity0.05 mg
PurityGreater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test
TypeRecombinant Proteins
Molecular Weight57.1 kD
SpeciesHuman
Molecule NameIRF5
Source/Expression SystemE. coli
NCBI Full Gene Nameinterferon regulatory factor 5
NCBI Gene AliasesSLEB10
FormatLyophilized
Research AreaApoptosis,Immunology

Specifications/Features

Format: Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.